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Research Participation Opportunities

The Chronic Pain After Moderate to
Severe TBI Multi-Site Project

The Characterization and Treatment of Chronic Pain after Moderate to Severe Traumatic Brain Injury Multi-Site project is a collaborative research study to gain knowledge on chronic pain and pain treatment after moderate to severe traumatic brain injury. Study participants must be already enrolled in the TBIMS project at one of the participating study sites. At the time of TBIMS follow-up interview, TBIMS participants will be invited to take part in interviews and surveys to gather detailed information on chronic pain, including identifying the most common types of pain, co-occurring pain conditions, treatments that have been more or less successful and learning from both individuals with TBI and providers what the facilitators and barriers are to appropriate pain treatment for those with TBI.

If you are interested in learning more about this study, please contact the Research Department: Clare Morey at 303-789-8621,

Biofeedback Treatment of Anxiety Associated
with Chronic SCI

Craig Hospital is currently recruiting participants with SCI for a research study to test an intervention designed to treat stress and anxiety.

Do you or someone you know have:

  • A diagnosis of tetraplegia and experience residual sensory or motor impairments?
  • The desire to reduce stress and anxiety?
  • Availability to complete a self-administered intervention twice a week for 4 weeks at home?

If you would like more information about this project or to see if you qualify, please call Bria MacIntyre at 303-789-8757,

Click here to see a flyer for this research study.

Brivaracetam to Reduce Neuropathic
Pain in Chronic SCI: A Pilot Trial

Craig Hospital and the University of Minnesota are studying the effects of an investigational drug with individuals that have a spinal cord injury and severe neuropathic pain. Participants will be studied over the course of three months. There will be three study visits, and we will ask you to take the investigational drug, complete survey assessments, and have two research MRIs and blood draws. Following completion of your study visits, you will be compensated for your time.

To participate you must:

  • Have completed inpatient rehabilitation and are living in the community
  • Have severe below-level neuropathic pain (daily average of 9/10 or 10/10)
  • Have tried and failed to achieve adequate pain relief with the use of other drugs
  • Not have progressive myelopathy
  • Not have a brain injury that limits ability to follow directions
  • Not be pregnant or lactating
  • Not have epilepsy
  • Not have impaired liver or renal function
  • Not have contraindications to Brivaracetam

If you are interested in learning more about this research opportunity, please contact Abby Welch in the Research Department at or 303-789-8039

Click here to see a flyer for this research study.

Craig Caregiver Assessment of Rewards and
Effort (C2ARE): Validation Study of a new tool
to assess caregiver distress and benefit

The purpose of this study is to test a newly developed measure designed to assess SCI-specific caregiver distress and benefit. Study participants will be asked to complete a quick survey by phone or online.

To be eligible, you must currently be:

  • providing assistance to a family member with SCI
  • 18 years of age or older, and
  • able to read and understand English

If you would like more information about this project or to see if you qualify, please contact Abby Welch at 303-789-8039,, or Jody Newman at 303-789-8639,

Click here to see a postcard for this research study.

Exploring Autoimmunity after Traumatic SCI: A Pilot Study

The purpose of this study is to explore if there are biomarkers of changes in the immune system after a traumatic spinal cord injury that may play a critical role in neurological recovery after spinal cord injury. Participants will complete questionnaires and provide a blood sample. Participants with spinal cord injury will be current inpatients at Craig Hospital and will be approached by study staff. However, we are also seeking participants WITHOUT spinal cord injury from the community.

To be eligible, you must:

  • Not have a spinal cord injury
  • Be between the ages of 18 and 89

If you are interested in hearing more about the study or finding out if you qualify, please contact Delaney Evans at

The Impact of Oral Health on Quality of Life, Participation and Health in People with Spinal Cord Injury

Craig Hospital is currently recruiting participants with spinal cord injury (SCI) for a research study on the impact of oral health on quality of life. Participants will take part in a one-time group discussion via Zoom, answering questions about your oral health and things that make it easier and/or harder to maintain your oral health after SCI. Participants will be compensated for their time.

You are eligible if you've had a SCI for at least a year, are 18 years or older, and speak English fluently.

If interested or to hear more information, please contact Abby Welch at 303-789-8039 or

Click here to see a flyer for this research study.